Table 3 Multivariable conditional logistic model to identify risk factors for Clostridioides difficile infection (CDI) due to the ribotype 027 strain

Gender male

1.02

0.85

1.23

0.839

Age > 65 years old

1.28

1.16

1.41

<0.001

BMI, kg/m2

0.99

0.99

1.00

0.055

Race, white

1.04

0.93

1.16

0.536

CCIS

1.01

0.99

1.03

0.440

Braden Scale

 No Risk

Ref

 Mild

1.19

1.09

1.31

<0.001

 Moderate

1.28

1.09

1.51

0.003

 High

1.31

1.09

1.58

0.004

Inflammatory Bowel Disease

0.53

0.40

0.71

<0.001

Diabetes Mellitus

1.02

0.93

1.13

0.632

Cancer

0.97

0.87

1.08

0.572

Cirrhosis

1.18

1.00

1.39

0.052

Gastrointestinal procedure

0.73

0.55

0.97

0.032

Nasal colonization MRSA

1.33

1.18

1.50

<0.001

Serum creatinine, >1.3 mg/dL

1.03

0.94

1.13

0.503

Peripheral WBC count, ≥11k/mm

1.48

1.36

1.61

<0.001

Serum albumin, < 3.5 g/dL

1.33

1.20

1.47

<0.001

PPIs

0.86

0.79

0.93

<0.001

H2RAs

0.94

0.84

1.05

0.282

High Risk Antibiotics time of exposure within 90 days

 None

Ref

 ≤ 5 days

1.13

1.01

1.26

0.036

 6–14 days

1.38

1.23

1.55

<0.001

 ≥ 14 days

1.56

1.34

1.82

<0.001

Epidemiological Classification

 Community associated

Ref

 Health Care Associated

1.24

1.12

1.38

<0.001

Undetermined

1.34

1.10

1.63

0.004