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Table 3 Subgroup analysis results by WHO region, work experience, sex, and age group for knowledge, attitude, and practice regarding AMR among HCWs

From: Global knowledge, attitudes, and practices towards antimicrobial resistance among healthcare workers: a systematic review and meta-analysis

Type

grouping

No. studies

No. examined

Overall frequency

(95%CI)

Heterogeneity

 

χ2

P-value

I² (%)

Tau-squared

Knowledge

WHO Region

African Region

47

12,737

60.5(53.8–67.2)

3869.19

< 0.001

98.8

0.0542

Eastern Mediterranean Region (EMRO)

22

5708

54.2(40.8–67.8)

3916.82

< 0.001

99.5

0.1031

South-East Asia Region (SEARO)

33

7161

53.6(43.0-64.1)

4873.26

< 0.001

99.3

0.0938

Western Pacific Region (WPRO)

6

3254

45.9(13.978.0)

1882.53

< 0.001

99.7

0.1596

European Region (EURO)

2

573

70.3(47.2–93.5)

30.67

< 0.001

96.7

0.0269

Work Experience

< 5 years

11

714

60.9(46.4–75.6)

226.90

< 0.001

95.6

0.0542

≥ 5 years

11

778

60.4(41.8–78.9)

492.22

< 0.001

98.0

0.0947

Sex

Male

25

2907

59.0(50.5–67.4)

635.63

< 0.001

96.2

0.0428

Female

26

3033

51.0(40.1–61.9)

1326.70

< 0.001

98.1

0.0769

Age group

< 30 years

11

1973

57.2(48.7–65.7)

136.99

< 0.001

92.7

0.0185

≥ 30 years

11

789

65.7 (50.9–80.5)

265.30

< 0.001

96.2

0.0552

Population type

HCWs

17

5434

62.9(52.4–73.5)

1394.78

< 0.001

98.9

0.0481

Students in Health Field

2

302

55.3(49.7–60.9)

0.67

0.412

0

0.0000

Medical Students

29

8065

56.4(46.5–66.3)

3114.63

< 0.001

99.1

0.0727

Physicians and Doctor

14

3338

52.4(42.3–62.6)

598.39

< 0.001

97.8

0.0364

Veterinarians and An

11

2120

50.1(36.4–63.8)

539.32

< 0.001

98.1%

0.0524

Pharmacists and Phar

30

7274

62.2(51.6–72.8)

5370.87

< 0.001

99.5

0.0858

Nurses and Nursing S

7

2900

56.5(50.4–62.6)

701.61

< 0.001

99.1

0.0685

Attitude

WHO Region

African Region

13

2277

61.8(44.8–78.9)

1497.85

< 0.001

99.2%

0.0974

Eastern Mediterranean Region (EMRO)

14

4424

64.5(56.3–72.8)

484.66

< 0.001

97.3%

0.0240

South-East Asia Region (SEARO)

19

3994

58.9(43.0-74.8)

4226.28

< 0.001

99.6%

0.1229

Western Pacific Region (WPRO)

5

2965

60.4(48.5–72.3)

10186.73

< 0.001

100.0

0.3639

Work Experience

< 5 years

7

506

77.8(65.2–90.5)

126.92

< 0.001

95.3

0.0268

≥ 5 years

7

528

65.3(40.6–89.9)

416.00 (

< 0.001

98.6

0.1087

Sex

Male

13

1059

59.9(42.2–77.5)

646.79

< 0.001

98.3

646.79

Female

13

1383

64.9(49.0-80.8)

1330.32

< 0.001

99.1

0.0823

Age group

< 30 years

7

668

68.5(50.0-87.1)

278.44

< 0.001

97.8

0.0603

≥ 30 years

7

537

72.6(57.9–87.3)

116.96

< 0.001

94.9

0.0358

Population type

HCWs

7

1777

66.5(53.8–79.2)

216.70

< 0.001

97.2

0.0285

Medical Students

16

5627

51.5(28.3–74.7)

11947.37

< 0.001

99.9

0.2229

Physicians and Doctor

1

291

67.5(62.1–72.9)

NA

NA

NA

NA

Veterinarians and An

3

439

51.8(37.3–66.4)

19.14

< 0.001

89.5

0.0147

Pharmacists and Phar

19

4347

63.0(54.9–74.1)

1674.93

< 0.001

98.9

0.0593

Nurses and Nursing S

5

1179

74.4(52.5–92.4)

551.54

< 0.001

99.3

0.0620

Practice

WHO Region

African Region

13

1923

39.1(23.6–54.5)

890.39

< 0.001

98.7

0.0785

Eastern Mediterranean Region (EMRO)

7

2267

41.0(21.2–60.8)

739.59

< 0.001

99.2

0.0710

South-East Asia Region (SEARO)

18

3480

58.4(43.4–73.3)

4546.19

< 0.001

99.6

0.1034

Western Pacific Region (WPRO)

3

2488

42.8(16.4–69.2)

210.84

< 0.001

99.1

0.0536

European Region (EURO)

2

411

56.6(43.1–70.1)

6.60

0.010

84.9

0.0081

Work Experience

< 5 years

7

506

48.8(20.9–76.7)

337.41

< 0.001

98.2

0.1379

≥ 5 years

7

506

39.4(9.04–69.4)

451.73

< 0.001

98.7

0.1609

Sex

Male

13

1010

46.7(28.4–65.0)

621.08

< 0.001

98.1

0.1089

Female

13

1154

48.9(31.6–66.3)

665.71

< 0.001

98.2

0.0968

Age group

< 30 years

7

668

56.0(33.0–79.0)

321.13

< 0.001

98.1

0.0933

≥ 30 years

7

537

43.2(12.0-74.3)

486.52

< 0.001

98.8

0.1732

Population type

HCWs

6

1410

44.9(34.8–55.0)

75.45

< 0.001

93.4

0.0147

Medical Students

11

2313

55.3(31.8–78.9)

4453.01

< 0.001

99.8

0.1584

Physicians and Doctor

4

1153

30.3(7.06–52.9)

336.30

< 0.001

99.1

0.0524

Veterinarians and An

3

389

53.5(26.6–80.4)

57.25

< 0.001

96.5

0.0543

Pharmacists and Phar

16

3137

53.7(38.1–69.4)

1873.70

< 0.001

99.2

0.0998

Nurses and Nursing S

3

2167

21.0(19.3–22.8)

2.02

0.365

0.9%

0.0000

  1. Abbreviation: NA, Not applicable