Fig. 1

The flow diagram of the outbreak investigation and implementation of interventions in this study. HICMS: the Hospital Infection Case Monitoring System; CRAB: Carbapenem resistant Acinetobacter baumannii; IPC: the infection prevention and control program; ICU: Intensive care unit; MDRO: multidrug-resistant organism; CSSD: the Central Sterile Supply Department; WGS: Whole genome sequencing analysis; MLST: Multi-locus sequence typing; SNP: Single-nucleotide polymorphism