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Table 3 Whole genome sequencing data for all isolates. Data is sorted by sampling date, isolates showing the cgMLST 2791 complex type are colored light grey.

From: Successful termination of a multi-year wastewater-associated outbreak of NDM-5-carrying E. coli in a hemato-oncological center

Sample ID

Sampling Date

MLST (Warwick) ST

cgMLST CT

Beta-Lactam Resistance Genes

Other Resistance Genes and Point Mutations

blaNDM-5

blaTEM-1

blaCTX-M-15

blaOXA-1

aac(6')-Ib-cr5

aac(3)-IId

mph(A)

sul1

sul2

dfrA12

dfrA17

ftsI_I336IKYRI

ftsI_N337NYRIN

glpT_E448K

gyrA_D87N

gyrA_S83L

parC_S80I

parE_S458A

Patient A

2018-05-15

617

12607

x

x

x

x

x

 

x

x

x

x

x

x

 

x

x

x

x

x

Patient B

2018-05-20

617

12607

x

x

x

x

x

 

x

x

x

x

x

x

 

x

x

x

x

x

Patient C

2018-08-24

167

2791

x

x

x

x

x

x

x

x

 

x

x

 

x

 

x

x

x

x

Patient D

2018-09-19

617

12607

x

 

x

x

x

 

x

x

x

x

x

x

 

x

x

x

x

x

Room 2-1

2018-09-25

617

12607

x

x

x

x

x

 

x

x

x

x

x

x

 

x

x

x

x

x

Room 1-1

2018-09-25

617

12607

x

 

x

x

x

 

x

x

x

x

x

x

 

x

x

x

x

x

Room 3-1

2018-10-01

167

2791

x

x

x

x

x

x

x

x

 

x

x

 

x

 

x

x

x

x

Patient E

2018-11-27

617

12607

x

 

x

x

x

 

x

x

x

x

x

x

 

x

x

x

x

x

Patient F

2019-07-03

617

12607

x

 

x

x

x

 

x

x

 

x

x

x

 

x

x

x

x

x

Room 1-2

2019-07-08

617

12607

x

 

x

x

x

 

x

x

 

x

x

x

 

x

x

x

x

x

Room 1-3

2019-09-09

617

12607

x

 

x

x

x

 

x

x

x

x

x

x

 

x

x

x

x

x

Patient G

2019-11-12

617

12607

x

 

x

x

x

 

x

x

x

x

x

x

 

x

x

x

x

x

Room 4-1

2019-11-14

617

12607

x

x

x

x

x

 

x

x

x

x

x

x

 

x

x

x

x

x

Room 5-1

2019-11-14

617

12607

x

 

x

x

x

 

x

x

x

x

x

x

 

x

x

x

x

x

Room 6-1

2019-11-18

167

2791

x

x

x

x

x

x

x

x

 

x

x

 

x

 

x

x

x

x

 

Virulence Genes

Genes encoding biofilm/acid-resistance regulators or tolerance to disinfectants and/or heavy metals

Sample ID

AslA

aamR:FN554766

anr

capU

csgA

fdeC

fyuA

hha

hlyE

hra

irp2

iss

iucC

iutA

nlpI

sitA

terC

traJ

traT

yehA

yehB

yehC

yehD

ymgB

qacEdelta1

terD

terZ

Patient A

x

 

x

 

x

x

x

x

x

 

x

x

x

x

x

x

x

x

 

x

x

x

x

x

x

  

Patient B

x

 

x

 

x

x

x

x

x

 

x

x

x

x

x

x

x

x

 

x

x

x

x

x

x

  

Patient C

x

x

 

x

x

x

x

x

x

x

x

x

  

x

 

x

 

x

 

x

x

x

x

x

  

Patient D

x

 

x

 

x

x

x

x

x

 

x

x

x

x

x

x

x

x

x

x

x

x

x

x

x

  

Room 2-1

x

 

x

 

x

x

x

x

x

 

x

x

x

x

x

x

x

x

 

x

x

x

x

x

x

  

Room 1-1

x

 

x

 

x

x

x

x

x

 

x

x

x

x

x

x

x

x

x

x

x

x

x

x

x

  

Room 3-1

x

x

 

x

x

x

x

x

x

x

x

x

  

x

 

x

 

x

 

x

x

x

x

x

  

Patient E

x

 

x

 

x

x

x

x

x

 

x

x

x

x

x

x

x

x

x

x

x

x

x

x

x

  

Patient F

x

 

x

 

x

x

x

x

x

 

x

x

x

x

x

x

x

x

x

x

x

x

x

x

x

  

Room 1-2

x

 

x

 

x

x

x

x

x

 

x

x

x

x

x

x

x

x

x

x

x

x

x

x

x

  

Room 1-3

x

 

x

 

x

x

x

x

x

 

x

x

x

x

x

x

x

x

x

x

x

x

x

x

x

  

Patient G

x

 

x

 

x

x

x

x

x

 

x

x

x

x

x

x

x

x

x

x

x

x

x

x

x

  

Room 4-1

x

 

x

 

x

x

x

x

x

 

x

x

x

x

x

x

x

x

 

x

x

x

x

x

x

  

Room 5-1

x

 

x

 

x

x

x

x

x

 

x

x

x

x

x

x

x

x

x

x

x

x

x

x

x

x

x

Room 6-1

x

x

 

x

x

x

x

x

x

x

x

x

  

x

 

x

 

x

 

x

x

x

x

x

  
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Antimicrobial Resistance & Infection Control

ISSN: 2047-2994

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