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Table 2 Antimicrobial susceptibility testing data according to EUCAST for all patient and environmental isolates. Minimum inhibitory concentrations are indicated in brackets. n.d.: not determined

From: Successful termination of a multi-year wastewater-associated outbreak of NDM-5-carrying E. coli in a hemato-oncological center

Antibiotic

Patient A

Patient B

Patient C

Patient D

Patient E

Patient F

Patient G

Room 1–1

Room 1–2

Room 1–3

Room 2–1

Room 3–1

Room 4–1

Room 5–1

Room 6–1

Ampicillin

R

R

R

R

R

R

R

R

R

R

R

R

R

R

R

Amoxicillin/clavulanic acid

R

R

R

R

R

R

R

R

R

R

R

R

R

R

R

Cefuroxime

R

R

R

R

R

R

R

R

R

R

R

R

R

R

R

Cefotaxime

R

R

R

R

R

R

R

R

R

R

R

R

R

R

R

Ceftazidime

R

R

R

R

R

R

R

R

R

R

R

R

R

R

R

Cefepime

R

R

R

R

R

R

R

R

R

R

R

R

R

R

R

Ceftolozane-Tazobactam

R

R

R

R

R

R

R

n.d

n.d

n.d

n.d

n.d

n.d

n.d

n.d

Ceftazidime-Avibactam

R

R

R

R

R

R

R

n.d

n.d

n.d

n.d

n.d

n.d

n.d

n.d

Meropenem

R [16]

R [16]

R [16]

R [16]

R [16]

R [16]

I [8]

I

R

I

R

R

I

I

R

Gentamicin

S

S

R

S

S

I

S

S

S

S

R

S

S

S

R

Tobramycin

R

R

R

R

R

R

R

n.d

n.d

n.d

n.d

n.d

n.d

n.d

n.d

Amikacin

S

S

S

S

S

I

S

n.d

n.d

n.d

n.d

n.d

n.d

n.d

n.d

Ciprofloxacin

R

R

R

R

R

R

R

R

R

R

R

R

R

R

R

Fosfomycin

S [2]

S [1]

S [1]

S [0.5]

S [0.5]

S [4]

S [1]

n.d

n.d

n.d

n.d

n.d

n.d

n.d

n.d

Tigecyclin

S [0.25]

S [0.125]

S [0.5]

S [0.25]

S [0.125]

S [0.25]

S [0.25]

n.d

n.d

n.d

n.d

n.d

n.d

n.d

n.d

Trimethoprim-Sulfamethoxazole

R

R

R

R

R

R

R

R

R

R

R

R

R

R

R

Colistin

S [0.25]

S [0.25]

S [0.25]

S [0.25]

S [0.25]

S [1]

S [1]

n.d

S [1]

n.d

n.d

n.d

n.d

n.d

S [1]