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Table 2 Overview of national and local IPC measures for MDR enterobacterales bacteria in Germany

From: Infection prevention and control without borders: comparison of guidelines on multidrug-resistant organisms in the northern Dutch-German cross-border region

IPC measures

KRINKO-DE

KOL

screening criteria

3MRGN

not recommended

4MRGN

patients who had

• recent healthcare contact in 4MRGN-endemic countries.

• contact with 4MRGN-positive patients.

• inpatient stay (> 3 days) in a high 4MRGN prevalence region within the past 12 months.

• patients

 o with positive history

 o transferred from foreign hospitals.

• immigrants from emergency reception centres

sampling site

rectal (wound and urine if needed)

rectal, urinary tract catheter, urine and known localization of the MRGN

management of carriers

3MRGN

contact precaution (single room/ cohort): only valid for E. coli and K. pneumoniae at risk wards1

4MRGN

contact isolation at all hospital wards

3MRGN

same as KRINKO2,3

4MRGN

contact-plus isolation

lifting the isolation

no recommendation

• 3 negative results on different days (1 week interval)

• weekly control series after lifting the isolation

readmission of a known MDRGN patient to a normal ward

3MRGN

uptake screening and basic hygiene

4MRGN

uptake screening and isolation

readmission of a known MDRGN patient to risk-wards

uptake screening and isolation

recommended PPE for HCWs

gloves and long-sleeved gown

• same as KRINKO for direct contact

• only hand disinfection if no contact.

• overcoat and trousers for very close contact.

• triple-layer medical mask if evidence of respiratory tract colonisation and direct patient contact.

  1. DE, Germany; HCW, healthcare worker; KRINKO, Kommission für Krankenhaushygiene und Infektionsprävention; MRGN, multidrug-resistant Gram-negative bacteria; KOL, Klinikum Oldenburg
  2. 1 Risk areas are defined after individual risk assessment depending based on the patient’s material and structural conditions. Intensive care wards, neonatology, and haematological-oncological wards are risk wards. For Serratia spp., isolation is recommended in neonatology wards
  3. 2 intensive care unit, dialysis, oncology and BMT
  4. 3 cohort isolation can only be carried out for patients with an MRGN of the same pattern (if necessary, consultation with the hygiene team)