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Table 1 Summary of studies on antibiotic consumption

From: Improving antibiotic utilization in West Africa: enhancing interventions through systematic review and evidence synthesis

Publication

Duration of study

Location

Health Care Level

Type of study population

Total No. of patients

Total antibiotics

Access Antibiotics

Watch Antibiotics

Not recommended

AMX

GEN

AMP

AMC

SXT

MET

AZM

CAM

CTX

CAZ

CRO

CIP

LVX

MEM

CXM

CFP-SUL

Abubakar et al. [93]

May–July 2016

Nigeria

Tertiary

Women who had obstetrics and gynaecology surgeries

248

1675.3 DDD per 100 bed days

–

5.6

-

754.6

–

615.1

–

–

–

–

44.4

11.6

-

-

227.4

–

Lakoh et al. [64]

February and October 2021

Sierra Leone

Secondary- and tertiary-care health facilities

Surgical prophylaxis individuals

753

117.9 DDD per 100 bed days

1.1

2.2

15.0

14.5

–

30.8

0.1

0.1

-

-

41.6

1.0

1.9

–

0.1

–

ALabi et al. [61]

January 2016–November 2021

Ghana

Secondary healthcare

In- and outpatients who attended the hospital

1 028 016

2 629 786.0 (mean; 256.7 ± 33 DDD/100 patients per year)

74.87

12.7

0.3

372.6

145.8

127.8

88.4)

39.9

0.1

0.004

41.9

82.9

5.9

0.5

287.4

–

Lakoh, Williams et al. [66]

March–October 2021

Sierra Leone

Tertiary

Patients admitted to medical or intensive care unit

468

66.9 DDD per 100 bed days

0.1

1.7

–

3.9

-

12.4

2.5

–

–

–

23.9

3.5

18.0

–

–

–

Below are Antibiotic consumption in Pediatric ward and Outpatients expressed in Days of Antibiotic Therapy/1000 Patient-Days and DDD per 1000 outpatient-days respectively

 

Chaw et al. [50]

January–December 2015

Gambia

Tertiary

All patients (aged > 28 days to 15 years) who received antibiotic therapy

917

670.7 Days of Antibiotic Therapy/1000 Patient-Days

37.1

164.2

103.0

4.0

1.4

18.0

–

–

–

–

121.1

8.7

–

–

–

–

Lakoh, John-Cole et al. [65]

April 2022

Sierra Leone

Tertiary

Pregnant women and lactating mothers, children and regular patients in the outpatient clinics

913

55.3 DDD per 1000 outpatient-days

21.9

0.01

0.04

4.67

-

7.94

0.87

4.09

–

–

0.00

4.70

1.51

–

3.04

–

  1. The table summarizes studies on antibiotic consumption in inpatients, expressed as Defined Daily Dose (DDD) per 100 bed-days, overall and/or for individual antibiotics, and divided by primary versus secondary/tertiary care settings. A was an outlier and was not added when computing the pooled antibiotic consumption for inpatients. However, it was added as part of the subgroup analysis of inpatients to understand the heterogeneity that exist between studies that took more than a year and those that took less than a year
  2. AMX, Amoxacillin; GEN, Gentamicin; AMP = Ampicillin; AMC = Amoxicillin-clavulanate; SXT = Sulfamethoxazoletrimethoprim; MET = Metronidazole; AZM = Azithromycin; CAM = Clarithromycin; CTX = Cefotaxime; CAZ = Ceftazidime; CRO = Ceftriaxone; CIP = Ciprofloxacin; LVX = Levofloxacin; MEM = Meropenem; CXM = Cefuroxime; CFP-SUL = Cefoperazone-Sulbactam
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Antimicrobial Resistance & Infection Control

ISSN: 2047-2994

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