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Table 3 Sensitivity analyses for the association between oral Vancomycin use and VRE incidence, assuming various time lag between antibiotic use and VRE incidence

From: Oral vancomycin use and incidence of vancomycin-resistant enterococci: time-series analysis

Sensitivity analyses

Coefficient

95% CI

P-value

1-month lag between antibiotic use and VRE incidence

0.0193

0.0038 to 0.0349

0.0145

2-month lag between antibiotic use and VRE incidence

0.0171

0.0005 to 0.0337

0.0435

3-month lag between antibiotic use and VRE incidence

0.0310

0.0141 to 0.0478

0.0003

No lag between antibiotic use and VRE incidence

0.0186

0.0022 to 0.0351

0.0267

Assuming time lags estimated from residuals of ARIMA models for each variable

0.0192

0.0031 to 0.0353

0.0194

  1. CI, confidence interval
  2. P-values indicating statistical significance are highlighted in bold
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Antimicrobial Resistance & Infection Control

ISSN: 2047-2994

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