An outbreak of blaKPC−4- and blaVIM−1-producing Klebsiella pneumoniae and Klebsiella variicola at a single hospital in South Korea

Table 2 Antimicrobial susceptibility profile of Klebsiella spp. co-harboring bla_KPC−4 and bla_VIM−1

Isolate ID	Species	Antimicrobial susceptibility test (MIC, µg/mL)								Related ARGs other than bla_KPC−4 and bla_VIM−1^*
Isolate ID	Species	MER	IPM	ERT	COL	GEN	TOB	CIP	LVX	Related ARGs other than bla_KPC−4 and bla_VIM−1^*
DSMCPE25	K. variicola	64	32	64	2	8	> 8	<=1	<=2	aac(6’)-Ib9, aadA1, aadA2, qnrA1
DSMCPE46	K. variicola	64	32	32	4	8	> 8	<=1	<=2	aac(6’)-Ib9, aadA1, aadA2, qnrA1
DSMCPE40	K. pneumoniae	8	16	8	64	8	> 8	2	2	mgrB, aac(6’)-Ib9, aadA1, qnrS1
DSMCPE42	K. pneumoniae	32	16	16	32	8	> 8	> 2	2	mgrB, aac(6’)-Ib9, aadA1, qnrS1
DSMCPE43	K. pneumoniae	32	16	16	64	8	> 8	> 2	4	mgrB, aac(6’)-Ib9, aadA1, qnrS1
DSMCPE50	K. pneumoniae	32	16	16	0.5	8	> 8	<=0.5	<=1	aac(6’)-Ib9, aadA1, qnrS1
DSMCPE56	K. pneumoniae	32	32	16	16	8	> 8	> 2	2	mgrB, aac(6’)-Ib9, aadA1, qnrS1
DSMCPE65	K. pneumoniae	64	32	32	32	8	> 8	> 2	4	mgrB, aac(6’)-Ib9, aadA1, qnrS1
DSMCPE136	K. pneumoniae	64	64	32	128	8	> 8	> 2	4	mgrB, aac(6’)-Ib9, aadA1, qnrS1

*Regarding mgrB gene, only isolates in which the truncated mutation was detected were listed
MIC: minimum inhibitory concentration, MER: meropenem, IPM: imipenem, ERT: ertapenem. COL: colistin, GEN: gentamicin, TOB: tobramycin, CIP: ciprofloxacin, LVX: levofloxacin

ISSN: 2047-2994