Development and validation of prediction models for nosocomial infection and prognosis in hospitalized patients with cirrhosis

Table 2 Details of NIs in derivation and external validation cohorts

Type of infection	Derivation cohort (n = 108)	External validation cohort (n = 52)	P value
NI diagnoses
SBP	45 (41.7)	21 (40.4)	0.88
Spontaneous bacteremia	10 (9.3)	2 (3.8)	0.34
UTI	9 (8.3)	13 (25.0)	< 0.01
C. difficile infection	2 (1.9)	1 (1.9)	1.00
Soft tissue/skin infection	7 (6.5)	2 (3.8)	0.72
Intra-abdominal infection	4 (3.7)	1 (1.9)	1.00
Secondary bacterial peritonitis	5 (4.6)	2 (3.8)	1.00
Unknown site infection¹	8 (7.4)	3 (5.8)	1.00
Other infections²	12 (11.1)	4 (7.7)	0.58
Pathogens
Bacteria	73 (67.6)	33 (63.5)	0.60
Fungus	10 (9.3)	8 (15.4)	0.25
MDR	7 (6.5)	10 (19.2)	0.01

The total number of infection sites may add up to > 100% because some patients have multiple infections
¹ Unknown site infection denotes the presence of fever and leukocytosis requiring antibiotic therapy without any identifiable source
² Other infections included meningitis (n = 5), bacterial enterocolitis (n = 3), and spontaneous bacterial empyema (n = 8)
Abbreviations: MDR, Multidrug Resistance; SBP, spontaneous bacterial peritonitis; UTI, urinary tract infection

ISSN: 2047-2994