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Table 4 Risk factors of S. aureus surgical site infections (SSI)

From: Staphylococcus aureus screening and preoperative decolonisation with Mupirocin and Chlorhexidine to reduce the risk of surgical site infections in orthopaedic surgery: a pre-post study

Variables

Monomicrobial

S. aureus SSI

n= 30

Surgical procedures without SSI

n= 5248

Odds Ratio

(CI 95%)

P value

Adjusted Odds Ratio (95% CI)

P value

Age in years, median (Q1-Q3)

64.5 (54 – 70)

68 (60 – 76)

0.98 (0.96 – 1.01)

0.119

  

Gender, n (%)

Male

20 (0.9)

2303 (99.1)

ref.

0.012

Female

10 (0.3)

2945 (99.7)

0.39 (0.183 – 0.84)

 

BMI in kg/m2, median (Q1-Q3)

n= 30

n= 2614

1.05

0.010

1.05 (1.0 – 1.1)

0.049

30.7 (28.1-41.8)

27.5 (23.2 – 32.5)

(1.01 – 1.10)

CCI, median (Q1-Q3)

1 (0 – 2)

0 (0 – 1)

1.36 (1.11 – 1.67)

0.003

 

0.034

ASA score, n (%)

  

n= 4539

 

0.273

1

4 (0.45)

878 (99.5)

ref.

 

2

15 (0.56)

2658 (99.4)

1.24 (0.41 - 3.74)

 

3 and 4

11 (1.1)

1003 (98.9)

2.41 (0.78 – 7.82)

 

Altemeier classification, n (%)

1

29 (0.5)

5209 (99.5)

ref.

0.205

2

1 (2.5)

39 (97.5)

4.61 (0.61 – 34.73)

 

Hospitalisation duration before the surgery in hours, median (Q1-Q3)

18 (17 – 21)

17 (16 – 19)

0.99 (0.99 – 1.02)

0.132

Duration of surgery in minutes, median

 

n= 5275

(Q1-Q3)

81 (67 – 118)

68 (52 – 88)

1.01 (1.01 – 1.02)

0.001

1.01 (1.00 – 1.02)

0.006

Type of surgery, n (%)

Hip (primary arthroplasty and revision)

8 (0.4)

2245 (99.6)

ref.

0.009

OS (of the UEF and others)

7 (1.7)

396 (98.3)

4.9 (1.79 – 13.76)

Knee (primary arthroplasty and revision)

15 (0.6)

2607 (99.4)

1.61 (0.68 – 3.82)

Site, n (%)

North

14 (1.3)

1063 (98.7)

ref.

<

South

16 (0.4)

4185 (99.6)

0.29 (0.14 – 0.60)

0.001

Period of surgery,

Period before

19 (0.8)

2427 (99.2)

2.01 (0.95 - 4.32)

0.061

n (%)

Period after

11 (0.4)

2821 (99.6)

ref.

 

Presence of preoperative screening, n (%)

n= 29

n= 5159

 

0.112

0.24 (0.08 – 0.73)

0.012

Yes

No

4 (0.29)

25 (0.66)

1387 (99.71)

3772 (99.34)

0.44 (0.15 – 1.25)

ref.

 

Result of preoperative screening, n (%)

n= 4

n= 1387

 

1.000

Positive

1 (0.28)

354 (99.7)

0.97 (0.10 - 9.40)

 

Negative

3 (0.29)

1033 (99.7)

ref.

 

Result of perioperative screeninga, n (%)

n= 1

n= 106

 

1.000

Positive

1 (10.0)

9 (90.0)

  

Negative

0

97 (100)

  
  1. Legend: Note that 21 preoperative screenings were carried out outside the intervention group and were included in this table
  2. ASA American Society of Anesthesiologists, BMI Body mass index, CCI Charlson comorbidity index, 95% CI Confidence interval at 95%, OS Osteosynthesis, Q1-Q3 Quartile1- Quartile3, SSI Surgical site infection, UEF Upper end of the femur
  3. aPerioperative screening = control screening among patients with a positive preoperative screening