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Table 2 Description of the surgical site infections according to the site and the period

From: Staphylococcus aureus screening and preoperative decolonisation with Mupirocin and Chlorhexidine to reduce the risk of surgical site infections in orthopaedic surgery: a pre-post study

Variables

SSI

Total

North

South

n = 100

North Total

n= 54

2014 – 2017

n= 24

2017 – 2020

n= 30

P value

South Total

n= 46

2014 – 2017

n= 18

2017 – 2020

n= 28

P value

Age (in years), median (Q1-Q3)

66 (56.5 – 74)

65 (49.5 – 72.5)

59.5 (45.5 – 70.5)

66 (51 – 75)

0.240

68.5 (60.25 – 74)

72 (64 – 78)

66 (59 (71.5)

0.057

Male gender, n(%)

61 (60.0)

33 (60.0)

12 (50.0)

21 (70.0)

0.134

28 (60.9)

11 (61.1)

17 (60.7)

0.979

BMI (in kg/m2), median (Q1-Q3)

28.9 (25.3 – 33.6)

28.8 (24.9 – 32.9)

30.2 (25.4 – 35.4)

28.1 (24.8 – 32.1)

0.134

29.6 (26.4 – 34.8)

28.4 (26.4 – 31.1)

31.3 (26.7 – 35.7)

0.405

CCI, median (Q1-Q3)

1 (0 – 2)

0 (0 – 2)

0.5 (0 – 2.5)

0 (0 – 2)

0.300

1 (0 – 2)

1 (0 – 2)

1 (0 – 2.5)

0.615

ASA score, n (%)

1

18 (18.0)

11 (20.4)

6 (25.0)

5 (16.7)

0.668

7 (15.2)

1 (5.6)

6 (21.4)

0.078

2

41 (41.0)

21 (38.9)

8 (33.3)

13 (43.3)

 

20 (43.5)

6 (33.3)

14 (50.0)

 

3

40 (40.0)

22 (40.7)

10 (41.7)

12 (40.0)

 

18 (39.1)

11 (61.1)

7 (25.0)

 

4

1 (1.0)

0

0

0

 

1 (2.2)

0

1 (3.6)

 

Altemeier classification, n (%)

1

99 (99.0)

53 (98.2)

23 (95.83)

30 (100)

0.444

46 (100)

18 (100)

28 (100)

-

2

1 (1.0)

1 (1.8)

1 (4.2)

0

 

0

0

0

 

Time between admission and the surgery (in hours), median (Q1-Q3)

18 (17 – 20)

19 (17 – 21)

19 (17 – 21.5)

19 (17 – 22)

0.680

17 (17 – 19)

17 (17 – 19)

17 (17 – 18.5)

0.881

Duration of the surgery (in minutes), median (Q1-Q3)

85 (65 – 125)

113 (75 – 152.75)

127 (88 – 153.5)

87 (68 – 144)

0.183

72 (59.3 – 100.3)

75 (65 – 106)

71 (58 – 81)

0.350

Type of surgery n (%)

OS of the UEF

0

0

0

0

0.038

0

0

0

0.074

Other OS

17 (17.0)

14 (25.9)

9 (37.5)

5 (16.7)

3 (6.5)

2 (11.1)

1 (3.6)

Knee prostheses

37 (37.0)

12 (22.2)

8 (33.3)

4 (13.3)

25 (54.3)

11 (61.1)

14 (50.0)

Hip prostheses

28 (28.0)

15 (27.8)

5 (20.8)

10 (33.3)

13 (28.3)

2 (11.1)

11 (39.3)

Revision of knee prosthesis

4 (4.0)

2 (3.7)

0

2 (6.7)

2 (4.4)

2 (11.1)

0

Revision of hip prosthesis

14 (14.0)

11 (20.4)

2 (8.3)

9 (30.0)

3 (6.5)

1 (5.6)

2 (7.1)

Smoking, n (%)

n= 98

   

0.079

n= 44

 

n= 26

0.682

19 (19.4)

12 (22.2)

8 (33.3)

4 (13.3)

 

7 (15.9)

2 (11.1)

5 (19.2)

 

Alcoholism, n (%)

n = 99

   

1.000

n= 45

 

n= 27

1.000

4 (4.0)

1 (1.9)

0

1 (3.3)

 

3 (6.7)

1 (5.6)

2 (7.4)

 

IV drug abuse, n (%)

0

        

Presence of HBP, n (%)

58 (58.0)

26 (48.2)

10 (41.7)

16 (53.3)

0.394

32 (69.6)

14 (77.8)

18 (64.3)

0.332

Presence of diabetes, n (%)

26 (26.0)

12 (22.2)

8 (33.3)

4 (13.3)

0.079

14 (30.4)

8 (44.4)

6 (21.4)

0.098

Presence of immunosuppression, n (%)

4 (4.0)

1 (1.8)

0

1 (3.3)

1.000

3 (6.5)

2 (11.1)

1 (3.6)

0.552

Presence of negligence, n (%)

3 (3.0)

1 (1.8)

0

1 (3.3)

1.000

2 (4.3)

0

2 (7.1)

0.513

Preoperative shower taken on D0, n (%)

n= 97

62 (63.9)

n= 53

39 (73.6)

16 (66.7)

n= 29

23 (79.3)

0.299

n= 44

23 (52.3)

2 (11.1)

n= 26

21 (80.8)

<0.001

Preoperative antibiotic prophylaxis: suitable molecule, n (%)

n= 96

n= 53

n= 23

 

0.434

n= 43

n= 16

n= 27

 

95 (99.0)

52 (98.1)

22 (95.7)

30 (100)

 

43 (100)

16 (100)

27 (100)

 

Operating theatre, n (%)

     

0.947

n= 44

n= 17

 

0.697

1 North

 

38 (70.4)

17 (70.8)

21 (70.0)

 

0

0

0

 

2 North

 

16 (29.6)

7 (29.2)

9 (30.0)

 

0

0

0

 

1 South

 

0

0

0

 

11 (25.0)

5 (31.3)

6 (21.4)

 

2 South

 

0

0

0

 

17 (38.6)

5 (31.3)

12 (42.9)

 

3 South

 

0

0

0

 

10 (22.7)

3 (18.8)

7 (25.0)

 

4 South

 

0

0

0

 

6 (13.6)

3 (18.8)

3 (10.7)

 

Position in the daily surgical schedule, n (%)

 

n= 98

   

0.234

n= 44

n= 16

 

0.780

1

36 (36.7)

26 (48.1)

9 (37.5)

17 (56.7)

 

10 (22.7)

4 (25.0)

6 (21.4)

 

2

39 (39.8)

18 (33.3)

9 (37.5)

9 (30.0)

 

21 (47.7)

9 (56.3)

12 (42.9)

 

3

13 (13.3)

4 (7.4)

3 (12.5)

1 (3.3)

 

9 (20.5)

3 (18.8)

6 (21.4)

 

4

6 (6.1)

4 (7.4)

3 (12.5)

1 (3.3)

 

2 (4.5)

0

2 (7.1)

 

5

4 (4.1)

2 (3.7)

0

2 (6.7)

 

2 (4.5)

0

2 (7.1)

 

Number of people present in the operating theatre, n (%)

 

n = 99

   

0.532

n= 45

n= 17

 

0.477

4

1 (1.0)

0

0

0

 

1 (2.2)

0

1 (3.4)

 

5

4 (4.0)

3 (5.6)

3 (12.5)

0

 

1 (2.2)

1 (5.9)

0

 

6

10 (10.1)

6 (11.1)

2 (8.3)

4 (13.3)

 

4 (8.9)

3 (17.7)

1 (3.6)

 

7

22 (22.2)

14 (25.9)

8 (33.3)

6 (20.0)

 

8 (17.8)

4 (23.5)

4 (14.3)

 

8

29 (29.3)

13 (24.1)

6 (25.0)

7 (23.3)

 

16 (35.6)

4 (23.5)

12 (42.9)

 

9

13 (13.1)

6 (11.1)

2 (8.3)

4 (13.3)

 

7 (15.6)

3 (17.7)

4 (14.3)

 

10

11 (11.1)

7 (13.0)

2 (8.3)

5 (16.7)

 

4 (8.9)

2 (11.8)

2 (7.1)

 

11

5 (5.1)

3 (5.5)

1 (4.2)

2 (6.7)

 

2 (4.4)

0

2 (7.1)

 

12

1 (1.0)

1 (1.8)

0

1 (3.3)

 

0

0

0

 

13

1 (1.0)

0

0

0

 

1 (2.2)

0

1 (3.6)

 

14

1 (1.0)

0

0

0

 

1 (2.2)

0

1 (3.6)

 

15

1 (1.0)

1 (1.8)

0

1 (3.3)

 

0

0

0

 

Presence of a postoperative haematoma, n (%)

n= 86

26 (30.2)

n= 47

13 (27.7)

n= 20

8 (40.0)

n= 27

5 (18.5)

0.104

n= 39

13 (33.3)

n= 15

4 (26.7)

n= 24

9 (37.5)

0.485

Postoperative anticoagulation, n (%)

n= 93

88 (94.6)

n= 50

47 (94.0)

n= 20

20 (100)

27 (90.0)

0.265

n= 43

41 (95.4)

n= 15

15 (100)

26 (92.9)

0.535

Non-compliance with postoperative recommendations, n (%)

n= 75

3 (4.0)

n= 42

1 (2.4)

n= 12

1 (8.3)

0

0.286

n= 33

2 (6.1)

n= 5

1 (20.0)

1 (3.6)

0.284

Time between surgery and the SSI (days), median (Q1-Q3)

29.5 (20 – 104)

21.5 (14-48)

19 (11-38)

29 (14-68)

0.136

32 (18-68)

32.5 (17 – 77)

32 (22-63.5)

0.773

Monomicrobial S. aureus SSI, n (%)

Superficial

4 (4.0)

1 (1.9)

0

1 (3.3)

0.286

3 (6.5)

2 (11.1)

1 (3.6)

1.000

Deep

26 (26.0)

13 (24.1)

10 (41.7)

3 (10.0)

13 (28.3)

7 (38.9)

6 (21.4)

CCFM SSI, n (%)

Superficial

4 (4.0)

1 (1.9)

0

1 (3.3)

0.381

3 (6.5)

2 (11.1)

1 (3.6)

1.000

Deep

39 (39.0)

20 (37.0)

13 (54.2)

7 (23.3)

19 (41.3)

10 (55.5)

9 (32.1)

All SSI, n (%)

Superficial

10 (10.0)

3 (5.6)

1 (4.2)

2 (6.7)

0.585

7 (15.2)

3 (16.7)

4 (14.3)

1.000

Deep

90 (90.0)

51 (94.4)

23 (95.8)

28 (93.3)

39 (84.8)

15 (83.3)

24 (85.7)

  1. Legend: ASA American Society of Anesthesiologists, BMI Body mass index, CCI Charlson comorbidity index, CCFM Cutaneous commensal flora microorganisms, HBP High blood pressure, IV Intravenous, OS Osteosynthesis, SSI Surgical site infection, UEF Upper end of the femur