Fig. 2

Distribution of sequence types and carbapenemase genes in carbapenemase-producing (CP) Escherichia coli (n = 26) and Klebsiella pneumoniae (n = 25) isolates. Geographical distribution of sequence types (ST) across the studied wastewater treatment plants (WWTP), distribution of carbapenemase genes in different STs and detection time of Carbapenemase-producing (A) Escherichia coli and (B) Klebsiella pneumoniae. The size of the circle reflects the number of isolates. Location tick marks on the map indicate that no isolates were detected in the corresponding WWTP. Isolate identification numbers (ID) are indicated (e.g., E2). ST, sequence type