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Table 3 Quantification of resistance gene expression after FMT in a culture-independent method

From: Faecal microbiota transplantation reduces amounts of antibiotic resistance genes in patients with multidrug-resistant organisms

 

Pre

Day 1

Day 7

Day 14

Day 28

p-value

VanA gene, log10 copies/mL

9.41 ± 2.34

8.59 ± 1.96

8.91 ± 2.70

7.82 ± 3.06

7.56 ± 3.02

0.047

blaKPC gene, log10 copies/mL

8.00 ± 2.62

6.83 ± 3.20

5.48 ± 2.92

6.01 ± 3.63

6.13 ± 4.18

0.063

blaOXA gene, log10 copies/mL

2.06 ± 1.83

1.83 ± 1.40

2.11 ± 1.87

2.56 ± 2.34

1.72 ± 0.82

0.774

blaNDM gene, log10 copies/mL

5.86 ± 3.63

4.04 ± 2.36

3.22 ± 0.81

3.24 ± 0.93

2.80 ± 0.79

0.048

Overall gene

9.64 ± 2.60

8.56 ± 2.53

8.52 ± 3.42

7.06 ± 3.90

6.04 ± 4.27

0.002

  1. FMT, faecal microbiota transplantation
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Antimicrobial Resistance & Infection Control

ISSN: 2047-2994

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