Table 1 Summary of reported mortality from literature
From: Mortality and Clostridium difficile infection: a review
Author | Study type | Country | 30-day mortality | Mortality at endpoint (other) | Participants |
|---|---|---|---|---|---|
Arvand, Hauri, Zaiss, Witte & Bettge-Weller (2009) | Prospective multicentre | Germany | 25% | - | 41 |
Bhangu, Bhangu, Nightingale & Michael (2010) | Cohort | UK | 38% | - | 158 |
Bishara, Peled, Pitlik & Samra (2008) | Case control | Israel | 15% case | - | Total 217 |
11.5% control (NS) | 52 cases | ||||
Cadena et al. (2010) | Cohort | US | 16% | 29% at 90 days | 129 |
Chung et al. (2010) | Cohort | Taiwan | 23.3% | 37.2% IHM | 86 |
Cloud, Noddin, Pressman, Hu & Kelly (2009) | Cohort | US | - | 12.1% IHM | 272 |
Dubberke et al. (2008) | Case control | US | - | 38% cases at 180 days | Cohort = 18,050 390 cases |
12% non-cases at 180 days | |||||
Fenner et al. (2008) | Cohort | Switzerland | 9% | - | 78 cases |
Gasperino et al. (2010) | Cohort | US | 16% cases, 5% controls | 20% cases IHM (cases) | 216,108 cases |
8% IHM (controls) | |||||
Gravel et al. (2009) | Prospective multicentre | Canada | 16.3% | - | 1430 |
5.7% attributable | |||||
Gulihar, Nixon, Jenkins & Taylor (2009) | Cohort | UK | 19% (cases) | 67% cases at 180 days | 170 cases |
9% match cohort | 29% matched cohort at 180 days | 3,247 matches | |||
Karas, Enoch & Aliyu (2010) | Review | UK | Not applicable | Not applicable | Not applicable |
Kenneally et al. (2007) | Cohort | US | 36.7% | - | 278 |
6.1% attributable | |||||
Labbe et al. (2008) | Cohort | Canada | 23.9% | - | 230 |
Loo et al. (2005) | Prospective multicentre | Canada | 24.8% | - | 1703 |
6.9% attributable | |||||
Lyytikainen et al. (2009) | Cohort | Finland | - | 14% at 30 days post-discharge | 8 093 |
Marra, Edmond, Wenzel & Bearman (2007) | Cohort | US | 17.2% at 14 days | 58 | |
27.6% IHM | |||||
McGowan et al. (2011) | Cohort | UK | 35.5% | 13.4% at 7 days | 2,571 |
20% at 14 days | |||||
58.7% at 1 year | |||||
Musher et al. (2005) | Prospective observational | US | - | 27% at 90 days | 207 |
Pant et al. (2010) | Cohort | US | 13.6% | - | 184 |
Shears, Prtak & Duckworth (2010) | Cohort | UK | 24.7% | 30.0% at 90 days | 227 |
Sundram et al. (2009) | Case control | UK | 14.4% at 28 days (extrapolated) | 11% at 3 days (027) | 97 cases |
3% at 3 days (106) | 97 controls | ||||
Wilson et al. (2010) | Cohort | UK | 35.9% | - | 128 |
Zilberberg, Shorr, Micek, Doherty & Kollef (2009) | Cohort. Secondary analysis of Kenneally et al. (2007) | US | 26.9% <65 years | - | 278 |
45.2% >65 |